When treated with a new inhibitor, a protein called ESI1 that mimics the symptoms of multiple sclerosis has demonstrated the ability to restore vital myelin sheaths that protect healthy axonal function.
Researchers have deciphered the complex interaction of various enzymes around the innate immune receptor Toll-like receptor 7 (TLR7), which plays an important role in protecting our body from viruses.
Rett syndrome is caused by mutations in the MECP2 gene, which is highly expressed in the brain and appears to play an important role in maintaining healthy neurons. The gene is located on the X chromosome, and the syndrome mainly affects girls.
Researchers have developed a new approach that turns a tumor cell's insidious defense mechanisms against itself, turning these "shield" molecules into targets for engineered chimeric antigen receptor (CAR) T cells programmed to attack the cancer.
Researchers have found that smooth muscle cells lining the arteries of people with atherosclerosis can develop into new cell types and take on cancer-like features, making the disease worse.
Researchers have discovered enzymes that, when mixed with red blood cells, can remove specific sugars that make up the A and B antigens in the human ABO blood group system.
We analyzed real-world clinical data to evaluate the impact of advanced treatments on patient outcomes after the most common procedure for atrial fibrillation: radiofrequency ablation.